Metabolism of polychlorinated biphenyls by Gunn rats: identification and serum retention of catechol metabolites.

@article{Haraguchi2004MetabolismOP,
  title={Metabolism of polychlorinated biphenyls by Gunn rats: identification and serum retention of catechol metabolites.},
  author={Koichi Haraguchi and Yoshihisa Kato and Nobuyuki Koga and Masakuni Degawa},
  journal={Chemical research in toxicology},
  year={2004},
  volume={17 12},
  pages={
          1684-91
        }
}
The tissue distributions of persistent metabolites of polychlorinated biphenyls (PCBs) in Wistar rats and homozygous uridine diphosphate glucuronosyltransferase (UGT) deficient Gunn rats exposed to 2,4,5,2',5'-pentachlorobiphenyl (CB101) and the commercial PCB mixture, Kanechlor-500 (KC500), were investigated. After exposure to CB101, four hydroxy and two methylsulfonyl (MeSO2) metabolites were detected in liver, lung, kidney, blood, and adipose tissues. One was identified as 3',4'-(OH)2-2,4,5… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-7 OF 7 CITATIONS

Chiral polychlorinated biphenyls: absorption, metabolism and excretion—a review

  • Environmental Science and Pollution Research
  • 2015
VIEW 8 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Methylsulfonyl polychlorinated biphenyls in fish from an electronic waste-recycling site in South China: levels, congener profiles, and chiral signatures.

Ying Zhang, Jiang-Ping Wu, +3 authors Bixian Mai
  • Environmental toxicology and chemistry
  • 2012
VIEW 1 EXCERPT
CITES BACKGROUND