Metabolism of methanogens

  title={Metabolism of methanogens},
  author={Michael Blaut},
  journal={Antonie van Leeuwenhoek},
  • M. Blaut
  • Published 2004
  • Chemistry, Medicine
  • Antonie van Leeuwenhoek
Methanogenic archaea convert a few simple compounds such as H2 + CO2, formate, methanol, methylamines, and acetate to methane. Methanogenesis from all these substrates requires a number of unique coenzymes, some of which are exclusively found in methanogens. H2-dependent CO2 reduction proceeds via carrier-bound C1 intermediates which become stepwise reduced to methane. Methane formation from methanol and methylamines involves the disproportionation of the methyl groups. Part of the methyl… Expand
The unique biochemistry of methanogenesis.
  • U. Deppenmeier
  • Biology, Medicine
  • Progress in nucleic acid research and molecular biology
  • 2002
This review focuses on the metabolic pathways of methanogenesis that are rather unique and involve a number of unusual enzymes and coenzymes and addresses questions related to the biochemical and genetic characteristics of the energy-transducing enzymes and to the mechanisms of ion translocation. Expand
Pathways of energy conservation in methanogenic archaea
The methyltetrahydromethanopterin:coenzyme M methyltransferase is a unique, reversible sodium ion pump that couples methyl transfer with the transport of Na+ across the cytoplasmic membrane, and Formylmethanofuran dehydrogenase is an reversible ions pump that catalyzes formylation and deformylation, of methanofuran. Expand
Trophic links between fermenters and methanogens in a moderately acidic fen soil.
The collective results suggest that this moderately acidic fen harbours phylogenetically diverse, moderately acid tolerant fermenters (both facultative aerobes and obligate anaerobes) that are trophically linked to methanogenesis. Expand
Methanothermobacter thermautotrophicus strain ΔH as a potential microorganism for bioconversion of CO2 to methane
Abstract Generally, all hydrogenotrophic methanogens can use the most important greenhouse gases (CO2 and CO) as sole carbon sources for energetic metabolism and biosynthesis of methane. AmongstExpand
Metabolism in hyperthermophilic microorganisms
Two So-reducing enzymes termed sulfhydrogenase and sulfide dehydrogenase have been purified from the cytoplasm of a hyperthermophile that is able to grow either with or without So, and a scheme for electron flow during the oxidation of carbohydrates and peptides and the reduction of So has been proposed. Expand
Thermodynamic and kinetic requirements in anaerobic methane oxidizing consortia exclude hydrogen, acetate, and methanol as possible electron shuttles
A simple theoretical model was used to describe the relationship between inter-bacterial distances and the energy lost due to concentration differences in consortia and predicted that members of Consortia thriving on low energy such as the MOC must adhere to each other and utilize a compound for the exchange of electrons that has a high permissible concentration range and a high diffusion coefficient and transfers as many electrons as possible per molecule. Expand
Genomic analysis of methanogenic archaea reveals a shift towards energy conservation
The genome-enabled reconstructed metabolisms reported here have significance to diverse anaerobic communities and have led to proposed substrate utilization not previously reported in isolation, such as formate and methanol metabolism in Mbac. Expand
Biotechnological aspects of anaerobic oxidation of methane coupled to sulfate reduction
Sulfate reduction (SR) can be used for the removal and recovery of metals and oxidized sulfur compounds from waste streams. Sulfate-reducing bacteria reduce oxidized sulfur compounds to sulfide.Expand
Metabolic characteristics of an aerobe isolated from a methylotrophic methanogenic enrichment culture
The results suggest that utilization of methanol by the mixed culture would involve metabolic interactions between the Pseudomonas sp. Expand
Function of homoacetogenesis on the heterotrophic methane production with exogenous H2/CO2 involved
Biological H2 production from anaerobic digestion (AD) is not a sustainable pathway, based on both the efficiency of energy recovery and operation possibility in practice. Because of this, the use ofExpand


Electron transfer reactions in methanogens
Abstract Methanogenic bacteria comprise a specialized group of obligately anaerobic microorganisms able to reduce a limited number of substrates to CH 4 . The intermediates involved in this reductionExpand
Autotrophic synthesis of activated acetic acid from two CO2 in Methanobacterium thermoautotrophicum
In a previous study with Methanobacterium thermoautotrophicum evidence was presented that methanogenesis and autotrophic synthesis of activated acetic acid from CO2 are linked processes. In thisExpand
The bioenergetics of methanogenesis.
The reduction of CO2 or any other methanogenic substrate to methane serves the same function as the reduction of oxygen, nitrate or sulfate to more reduced products. These exergonic reactions areExpand
Acetate and CO2 assimilation by Methanothrix concilii
The metabolic properties of Methanothrix concilii are closely related to those of Methanosarcina barkeri, and the origin of carbon atoms in glutamate, proline, and arginine showed that an incomplete tricarboxylic acid cycle operating in the oxidative direction was used for their biosynthesis. Expand
Methyl-coenzyme M reductase and other enzymes involved in methanogenesis from CO2 and H2 in the extreme thermophile Methanopyrus kandleri
Methanopyrus kandleri belongs to a novel group of abyssal methanogenic archaebacteria that can grow at 110°C on H2 and CO2 and that shows no close phylogenetic relationship to any methanogen known soExpand
Methane from acetate
  • J. Ferry
  • Medicine, Biology
  • Journal of bacteriology
  • 1992
The current understanding of the methanogenic fermentation of acetate provides impressions of nature's novel solutions to problems of methyl transfer, electron transport, and energy conservation. Expand
CO2 fixation in acetogenic bacteria: Variations on a theme
Emphasis is placed upon the acetyl CoA pathway in acetogenic bacteria, but important advances in the study of other strict anaerobes are also considered. Expand
Anabolic Pathways in Methanogens
Even though the methanogens are morphologically and nutritionally diverse, every major phylogenetic group includes some autotrophic species. Even among methanogens that require an organic carbonExpand
Identification of methyl coenzyme M as an intermediate in methanogenesis from acetate in Methanosarcina spp
Results indicate that CH3-S-CoM is an intermediate in the metabolism of acetate to methane in this organism, similar to that of CD3H to CD2H2. Expand
Methyltetrahydromethanopterin as an intermediate in methanogenesis from acetate in Methanosarcina barkeri
Cell extracts (100,000×g) of acetate grown Methanosarcina barkeri (strain MS) catalyzed CH4 and CO2 formation from acetyl-CoA with specific activities of 50 nmol·min-1·mg protein-1. CH4 formation wasExpand