Metabolism of malondialdehyde by rat liver aldehyde dehydrogenase.


Mammalian liver contains a group of pyridine nucleotide linked aldehyde dehydrogenases [E.C.] which are present in high specific activity and possess wide substrate specificities. Malondialdehyde (MDA), a difunctional three-carbon aldehyde thought to be toxic, is generated during membrane lipid peroxidation in hepatocytes. The role of aldehyde… (More)


  • Presentations referencing similar topics