Metabolism of immunoglobulin A in lactating mice: origins of immunoglobulin A in milk.

@article{Halsey1982MetabolismOI,
  title={Metabolism of immunoglobulin A in lactating mice: origins of immunoglobulin A in milk.},
  author={John F. Halsey and Cecily Mitchell and Ralf Meyer and John J. Cebra},
  journal={European journal of immunology},
  year={1982},
  volume={12 2},
  pages={
          107-12
        }
}
The metabolism of albumin and IgA was studied in normal and lactationg mice. Lactation resulted in significant changes in the metabolism of these proteins. The serum albumin concentration was lowered from 47 mg/ml in normals to 24 mg/ml in lactating mice. However, only a slight decrease in the serum concentration of IgA was observed during lactation. The proportion of polymeric and monomeric IgA in serum and milk was evaluated by gel exclusion chromatography. The onset of lactatin led to a rise… CONTINUE READING
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