Metabolism of ciclesonide in the upper and lower airways: review of available data

@inproceedings{Nave2008MetabolismOC,
  title={Metabolism of ciclesonide in the upper and lower airways: review of available data},
  author={Ruediger Nave and Nigel McCracken},
  booktitle={Journal of asthma and allergy},
  year={2008}
}
Ciclesonide is a novel corticosteroid (CS) for the treatment of asthma and allergic rhinitis. After administration, the parent compound ciclesonide is converted by intracellular airway esterases to its pharmacologically active metabolite desisobutyryl-ciclesonide (des-CIC). We investigated the in vitro activation of ciclesonide and further esterification of… CONTINUE READING