Metabolism of boswellic acids in vitro and in vivo.

  title={Metabolism of boswellic acids in vitro and in vivo.},
  author={Phillip Kr{\"u}ger and Rambod Daneshfar and Gunter P Eckert and Jochen Klein and Dietrich A Volmer and Ute Bahr and Walter E. M{\"u}ller and M. Karas and Manfred Schubert-Zsilavecz and Mona Abdel-Tawab},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  volume={36 6},
Boswellia serrata resin dry extract is among the few herbal remedies designated with an orphan drug status for the treatment of peritumoral brain edema. In addition, boswellic acids (BAs), the main active ingredients of B. serrata extracts, have potent anti-inflammatory properties, and may represent promising agents for the treatment of inflammatory diseases. Pharmacokinetic studies, however, revealed poor bioavailability, especially of 11-keto-beta-boswellic acid (KBA) and 3-acetyl-11-keto… CONTINUE READING


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Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers

  • V Sterk, B Büchele, T Simmet
  • Planta Med
  • 2004
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