Metabolism of arsenobetaine in mice, rats and rabbits.

@article{Vahter1983MetabolismOA,
  title={Metabolism of arsenobetaine in mice, rats and rabbits.},
  author={Marie Vahter and Erminio Marafante and Lennart Dencker},
  journal={The Science of the total environment},
  year={1983},
  volume={30},
  pages={197-211}
}
The distribution, retention and biotransformation of arsenobetaine, the most common organic arsenic compound in fish and crustacea, have been studied in mice, rats and rabbits by use of synthesized 73As-labelled arsenobetaine. Orally administered arsenobetaine was almost completely absorbed from the gastro-intestinal tract in mice. The urinary excretion for 3 days following intravenous injection was about 75% of the dose in the rabbits and more than 98% in the mice and rats. The rate of… CONTINUE READING
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