Metabolism of antithrombin III (heparin cofactor) in man: effects of venous thrombosis and of heparin administration

@article{Collen1977MetabolismOA,
  title={Metabolism of antithrombin III (heparin cofactor) in man: effects of venous thrombosis and of heparin administration},
  author={Désiré Collen and John A. Schetz and Fr{\'e}d{\'e}rique De Cock and Erik Holmer and Marc Verstraete},
  journal={European Journal of Clinical Investigation},
  year={1977},
  volume={7}
}
Abstract. The metabolism of human antithrombin III (heparin cofactor) was studied in four control subjects, in four subjects with peripheral obliterative arterial disease, in six patients with recent venous thrombosis and in one patient with clinically severe haemophilia A. The labelled antithrombin III had a high specific activity (5.75 units/mg) and displayed a single band on SDS‐polyacrylamide gel electrophoresis. On Sephadex G‐100 gel filtration the labelled material eluted in the same… Expand
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