Metabolism of aflatoxin B1 by rat hepatic microsomes induced by polyhalogenated biphenyl congeners.

@article{Halvorson1985MetabolismOA,
  title={Metabolism of aflatoxin B1 by rat hepatic microsomes induced by polyhalogenated biphenyl congeners.},
  author={M R Halvorson and Timothy D Phillips and Stephen Safe and Larry W Robertson},
  journal={Applied and environmental microbiology},
  year={1985},
  volume={49 4},
  pages={882-6}
}
The metabolism of aflatoxin B1 to aflatoxins M1 and Q1 by rat liver microsomes from animals pretreated with polychlorinated or polybrominated biphenyl congeners depended on the structure of the halogenated biphenyl inducers. Microsomes from rats treated with phenobarbital (PB) or halogenated biphenyls that exhibit PB-type activity preferentially enhanced… CONTINUE READING