Metabolism of Lp(a): assembly and excretion.

  title={Metabolism of Lp(a): assembly and excretion.},
  author={Gerhard M. Kostner and Xingde Wo and Sabine Frank and Karam Maximilien Kostner and Richard Zimmermann and Ernst Steyrer},
  journal={Clinical genetics},
  volume={52 5},
Lp(a) is one of the most atherogenic lipoproteins, and we know much more about the pathophysiology of Lp(a) than about its physiological function and metabolism. From our previous investigations and the new results reported here, we propose the following model of Lp(a) metabolism: apo(a) is biosynthesized in liver cells and the size of the isoform… CONTINUE READING