Metabolism of DHEA in postmenopausal women following percutaneous administration.

  title={Metabolism of DHEA in postmenopausal women following percutaneous administration.},
  author={Fernand Labrie and Alain B{\'e}langer and Patrick B{\'e}langer and Ren{\'e} B{\'e}rub{\'e} and C. James Martel and Leonello Cusan and Jos{\'e} Luis Santos G{\'o}mez and Bernard Candas and V{\'e}ronique Chaussade and Isabelle Castiel and Claire Deloche and Jacques Leclaire},
  journal={The Journal of steroid biochemistry and molecular biology},
  volume={103 2},
The marked decline in serum dehydroepiandrosterone (DHEA) with age is believed to play a role in health problems associated with aging, these health issues being potentially preventable or reversible by the exogenous administration of DHEA. In the present study, liquid chromatography/mass spectrometry/mass spectrometry (LC/MS/MS) and gas chromatrography/mass spectrometry (GC/MS) were used to measure the serum levels of DHEA and 11 of its metabolites in seventy-five 60-65-year-old Caucasian… CONTINUE READING
46 Citations
22 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 46 extracted citations


Publications referenced by this paper.
Showing 1-10 of 22 references

Is DHEA a hormone? Starling Review

  • F. Labrie, V. Luu-The, A. Bélanger, S.-X. Lin, J. Simard, C. Labrie
  • J. Endocrinol. 187
  • 2005
2 Excerpts

Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age

  • J. J. Nolan, J. C. Nelson, S. S. Yen
  • J . Clin . Endocrinol . Metab .
  • 2000

Inac - tivation of androgens by UDPglucuronosyltransferase enzymes in humans ,

  • G. Pelletier A. Bélanger, F. Labrie, O. Barbier, S. Chouinard
  • Trends Endocrinol . Metab .
  • 1996

Metabolic effects of 12 - month percutaneous DHEA replacement therapy in post - menopausal women

  • L. Cusan, J. L. Gomez, A. Bélanger, F. Labrie
  • J . Endocrinol .
  • 1994

Similar Papers

Loading similar papers…