Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency

@article{Gro1989MetabolismOD,
  title={Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency},
  author={Marie-Luise Gro\ss and Sarah Reiter and Nepomuk Z{\"o}llner},
  journal={Klinische Wochenschrift},
  year={1989},
  volume={67},
  pages={1205-1213}
}
D-ribose was administered orally or intravenously over at least 5 h to eight healthy volunteers and five patients with myoadenylate deaminase deficiency. Intravenous administration rates were 83, 167, and 222 mg/kg/h, which were well tolerated but oral administration of more than 200 mg/kg/h caused diarrhea. The average steady state serum ribose level ranged between 4.8 mg/100 ml (83 mg/kg/h, oral administration) and 81.7 mg/100 ml (222 mg/kg/h, intravenous administration). Serum glucose level… CONTINUE READING

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