Metabolism of [14C]glucose by postimplantation mouse embryos in vitro.

  title={Metabolism of [14C]glucose by postimplantation mouse embryos in vitro.},
  author={J R Clough and David G Whittingham},
  journal={Journal of embryology and experimental morphology},
Carbon dioxide and lactate production from [14C]glucose were measured for post-implantation mouse embryos aged 6 to 9 1/2 days post coitum in static cultures with a defined medium. The rate of metabolism increased rapidly and paralleled the increase in protein content indicating a fairly uniform rate of metabolism throughout the period. At all stages studied more than 90% of the glucose utilized was converted to lactate. Over a quarter of carbon dioxide produced was derived from the C-1… CONTINUE READING

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