Metabolism in Porifera. VII. Conversion of [7,7-3H2]-fucosterol into calysterol by the spongeCalyx niceaensis

  title={Metabolism in Porifera. VII. Conversion of [7,7-3H2]-fucosterol into calysterol by the spongeCalyx niceaensis},
  author={Luigi Minale and Raffaele Riccio and O. Scalona and Guido Sodano and Ernesto Fattorusso and Silvana Magno and Luciano Mayol and Ciro Santacroce},
The spongeCalyx niceaensis metabolizes administered [7,7-3H2]-fucosterol to produce labelled calysterol, the principal sterol component of the sponge, possessing the unique feature of a cyclopropene ring bridging C23,24. 
6 Citations

Tables and Topics from this paper

The diversity of marine sterols and the role of algal bio-masses; from facts to hypothesis
A review is presented in which the molecules dissolved in sea water, or found in marine organisms are considered with particular reference to algal production, and to the bio-ecological significance of the main sterols.
Porifera (Sponges)–1
The article contains sections titled: Overview of the Universe of Sponges Metabolites of Calcarea (Calcareous Sponges) General Characteristics of Calcarea Fatty Acids Sterols
Antitumor Profile of Carbon-Bridged Steroids (CBS) and Triterpenoids
This review focuses on the rare group of carbon-bridged steroids (CBS) and triterpenoids found in various natural sources such as green, yellow-green, and red algae, marine sponges, soft corals, ascidians, starfish, and other marine invertebrates, to identify possible promising sources for pharmacologists and the pharmaceutical industry.
In Silico Prediction of Steroids and Triterpenoids as Potential Regulators of Lipid Metabolism
This review focuses on a rare group of steroids and triterpenoids that share common properties as regulators of lipid metabolism and related processes such as anti-hyperlipoproteinemic activity, as well as the treatment of atherosclerosis, lipoprotein disorders, or inhibitors of cholesterol synthesis.
Extensive research has been carried out from last decades to discover potential constituents from plant sources. Stigmasterol is an important constituent and has been isolated from plants. It is


The conversion of 24-ethylidene-sterols into poriferasterol by Ochromonas malhamensis
The 24-ethylidene-sterols fucosterol, 28-isofucosterol and 5α-strigmasta-7,Z-24(28)-dien-3β-ol are converted into poriferasterol by Ochromonas malhamensis, the efficiency of conversion being
Metabolism in porifera-V, biosynthesis of 19-Nor-Stanols: Conversion of cholesterol into 19-nor-cholestanols by the spongeAxinella polypoides
La spugnaAxinella polypoides suggerisce che questi unici stanoli si originano da steroli dietarici per rimozione del metile in 10.
Marine sterols with a new pattern of side-chain alkylation from the sponge Aplysina(=Verongia)Aerophoba
The principal sterols of the marine sponge Aplysina(=Verongia)aerophoba, aplysterol and 24,28-didehydroaplysterol are characterized as 26-methyl homologues of 24-methyl- and 24-methylene-cholesterol,
Marine sterols: unique 3β-hydroxymethyl-A-nor-5α-steranes from the sponge Axinella verrucosa
The total sterol content of the marine sponge Axinella verrucosa is a mixture of unique stanols containing a 3β-hydroxymethyl-A-nor-5α-cholestane nucleus with conventional C8, C9, and C10 side-chains.
Calysterol: A C29 cyclopropene-containing marine sterol from the sponge Calyx nicaensis
Abstract From an extract of Calyx nicaensis calysterol ( 1 ), a new C 29 cyclopropene-containing sterol, has been isolated and its structure elucidated.
Marine sterols: 19-nor-stanols from the sponge Axinella polypoides
The total sterol content of the marine sponge Axinella polypoides is a mixture of 19-nor-stanols, in which the major resolved component has been fully characterized (as the acetate) as
Metabolism in porifera IV. Biosynthesis of the 3β-Hydroxymethyl-A-nor-5α-Steranes from cholesterol byAxinella verrucosa
La spugnaAxinella verrucosa trasforma il [4-14C]-colesterolo nel 3β-idrossimetil-A-nor-5α-colestano (1) e suggerisce che questi unici stanoli si originino principalmente per modificazione di steroli dietarici.