Metabolism and transport of gamma-carboxyglutamic acid.

  title={Metabolism and transport of gamma-carboxyglutamic acid.},
  author={Dhavtm V. Shah and J K Tews and Alfred E. Harper and John W Suttie},
  journal={Biochimica et biophysica acta},
  volume={539 2},
gamma-Carboxyglutamic acid residues have beeh shown to be present in prothrombin, the other vitamin K-dependent clotting factors, and more recently in bone and kidney proteins. This amino acid is formed by a posttranslational vitamin K-dependent carboxylation of glutamyl residues in polypeptide precursors of these protens. It has now been demonstrated that… CONTINUE READING