Metabolism and release of glutamate in cerebellar granule cells cocultured with astrocytes from cerebellum or cerebral cortex.

@article{Westergaard1991MetabolismAR,
  title={Metabolism and release of glutamate in cerebellar granule cells cocultured with astrocytes from cerebellum or cerebral cortex.},
  author={Niels Westergaard and Hanne Fosmark and Arne Schousboe},
  journal={Journal of neurochemistry},
  year={1991},
  volume={56 1},
  pages={59-66}
}
Cerebellar granule cells were cocultured with astrocytes from either cerebral cortex or cerebellum in two different systems. In one system the cells were plated next to each other only sharing the culture medium (separated cocultures) and in the other system the granule cells were plated on top of a preformed layer of astrocytes (sandwich cocultures). Using astrocytes from cerebellum, granule cells developed morphologically and functionally showing a characteristic high activity of the… CONTINUE READING

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