Metabolism and effects on platelet function of the purified eicosapentaenoic and docosahexaenoic acids in humans.

@article{Schacky1985MetabolismAE,
  title={Metabolism and effects on platelet function of the purified eicosapentaenoic and docosahexaenoic acids in humans.},
  author={C von Schacky and Peter C. Weber},
  journal={The Journal of clinical investigation},
  year={1985},
  volume={76 6},
  pages={2446-50}
}
Metabolism and effects on platelet function of 6 g/d for 6 d of either eicosapentaenoic acid (EPA, C20:5 omega-3) or docosahexaenoic acid (DCHA, C22:6 omega-3) in volunteers were compared in a randomized crossover study. Incorporation kinetics revealed that EPA appeared in plasma free fatty acids and plasma phospholipids after 4 h, but was not incorporated into platelet phosphatidylcholine and -ethanolamine until day 6. This indicates that platelet fatty acid composition does not immediately… CONTINUE READING
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