Metabolism and ecology of purine alkaloids.

  title={Metabolism and ecology of purine alkaloids.},
  author={Ana Anaya and Roc{\'i}o Cruz-Ortega and George R. Waller},
  journal={Frontiers in bioscience : a journal and virtual library},
In this review, the biosynthesis, catabolism, ecological significance, and modes of action of purine alkaloids particularly, caffeine, theobromine and theophylline in plants are discussed. In the biosynthesis of caffeine, progress has been made in enzymology, the amino acid sequence of the enzymes, and in the genes encoding N-methyltransferases. In addition, caffeine-deficient plants have been produced. The ecology of purine alkaloids has not proved to be particularly promising. However… CONTINUE READING
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