Metabolism and distribution of intramolecular excimer-forming dipyrenebutanoyl glycerophospholipids in human fibroblasts. Marked resistance to metabolic degradation.

@article{Kasurinen1995MetabolismAD,
  title={Metabolism and distribution of intramolecular excimer-forming dipyrenebutanoyl glycerophospholipids in human fibroblasts. Marked resistance to metabolic degradation.},
  author={J Kasurinen and Pentti Somerharju},
  journal={Biochemistry},
  year={1995},
  volume={34 6},
  pages={2049-57}
}
Metabolism and intracellular distribution of fluorescent 1, 2-dipyrenebutanoyl derivatives of phosphatidylcholine, -ethanolamine, and -serine and phosphatidic acid (diPyr4PC, -PE, -PS, and -PA, respectively) in human skin fibroblasts (HF) has been studied. When HF cells were co-incubated with phospholipid vesicles containing diPyr4PC at 8 degrees C, considerable amounts of fluorescent lipid were incorporated into the cells. This incorporation occurred mainly by spontaneous diffusion, since 10… CONTINUE READING