Metabolism and cellular functions of IP6: a review.

  title={Metabolism and cellular functions of IP6: a review.},
  author={Abulkalam M. Shamsuddin},
  journal={Anticancer research},
  volume={19 5A},
Inositol hexaphosphate (IP6) has a demonstrably effective anti-cancer action against a variety of experimental tumors. However, the mechanisms of its actions are yet to be completely discerned. Studies in my laboratory have shown that IP6 is rather rapidly absorbed by rats in vivo. Ion exchange chromatography demonstrates the presence of inositol and IP1-6 in gastric epithelial cells as early as within 1 h of intragastric 3H-IP6 administration. The metabolized IP6, in the form of inositol and… CONTINUE READING
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