Metabolism and antiproliferative effects of sulforaphane and broccoli sprouts in human intestinal (Caco-2) and hepatic (HepG2) cells


The purpose of this work was to study the absorption and metabolism of sulforaphane (SFN) from broccoli sprouts, their major glucosinolate glucoraphanin and its hydrolysis product SFN. This was done by monitoring SFN’s main metabolites, i.e. SFN, SFN-glutathione and SFN-cysteine, in two different cell models of absorption and metabolism (Caco-2 colorectal… (More)
DOI: 10.1007/s11101-015-9422-4

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