Metabolism and Renal Effects of Enflurane in Man

@article{Cousins1976MetabolismAR,
  title={Metabolism and Renal Effects of Enflurane in Man},
  author={Michael Cousins and L R Greenstein and Ben A. Hitt and Richard I. Mazze},
  journal={Anesthesiology},
  year={1976},
  volume={44},
  pages={44-53}
}
The metabolism and renal effects of enflurane were studied during and after anesthesia in ten surgical patients without renal disease; ten control patients received halothane. Enflurane was metabolized to inorganic fluoride with a mean peak serum level of 22.2 ± 2.8 µM four hours after anesthesia. Urinary inorganic and organic fluoride excretions were increased but oxalic acid excretion was not. suggesting that the latter is not an enflurane metabolite. Postanesthetic renal function, including… 

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