Metabolism and Functions of Phosphatidylserine in Mammalian Brain

@article{Mozzi2003MetabolismAF,
  title={Metabolism and Functions of Phosphatidylserine in Mammalian Brain},
  author={Riccardo Mozzi and Sandra Buratta and Gianfrancesco Goracci},
  journal={Neurochemical Research},
  year={2003},
  volume={28},
  pages={195-214}
}
Phosphatidylserine (PtdSer) is involved in cell signaling and apoptosis. The mechanisms regulating its synthesis and degradation are still not defined. Thus, its role in these processes cannot be clearly established at molecular level. In higher eukaryotes, PtdSer is synthesized from phosphatidylethanolamine or phosphatidylcholine through the exchange of the nitrogen base with free serine. PtdSer concentration in the nervous tissue membranes varies with age, brain areas, cells, and subcellular… CONTINUE READING
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