Metabolism, distribution and excretion of purified human chorionic gonadotropin and its subunits in man.

@article{Wehmann1984MetabolismDA,
  title={Metabolism, distribution and excretion of purified human chorionic gonadotropin and its subunits in man.},
  author={R E Wehmann and Sania Amr and Caterina Rosa and Bruce C. Nisula},
  journal={Annales d'endocrinologie},
  year={1984},
  volume={45 4-5},
  pages={291-5}
}
We have characterized the distribution, metabolism and excretion of hCG and its subunits in normal human subjects. The initial apparent volume of distribution was the same for hCG, hCG beta, and hCG alpha. Their disappearance curves fit a two-component exponential model, and calculations indicated that both the rapid and slow phase half-times of hCG are approximately 10-fold greater than those of hCG beta and 30-fold greater than those of hCG alpha. Despite the more rapid metabolic clearance… CONTINUE READING

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