Metabolic syndrome is related to polyneuropathy and impaired peripheral nerve function: a prospective population-based cohort study.

@article{Hanewinckel2016MetabolicSI,
  title={Metabolic syndrome is related to polyneuropathy and impaired peripheral nerve function: a prospective population-based cohort study.},
  author={Rens Hanewinckel and Judith Drenthen and Symen Ligthart and Abbas Dehghan and O. H. Franco and Albert Hofman and M. Arfan Ikram and Pieter Antoon van Doorn},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2016},
  volume={87 12},
  pages={1336-1342}
}
OBJECTIVE Diabetes mellitus is a known risk factor for polyneuropathy, but the role of pre-diabetes and metabolic syndrome remains unclear. We aimed to investigate the role of these factors in a community-dwelling middle-aged and elderly population. METHODS 1256 participants of the population-based Rotterdam Study (mean age 70.0, 54.5% females) were screened for polyneuropathy with a questionnaire, neurological examination and nerve conduction studies. Data on type 2 diabetes and components… CONTINUE READING