Metabolic syndrome in rheumatic diseases: epidemiology, pathophysiology, and clinical implications

@article{Sidiropoulos2008MetabolicSI,
  title={Metabolic syndrome in rheumatic diseases: epidemiology, pathophysiology, and clinical implications},
  author={Prodromos I Sidiropoulos and Stylianos A Karvounaris and Dimitrios T. Boumpas},
  journal={Arthritis Research & Therapy},
  year={2008},
  volume={10},
  pages={207 - 207}
}
Subjects with metabolic syndrome--a constellation of cardiovascular risk factors of which central obesity and insulin resistance are the most characteristic--are at increased risk for developing diabetes mellitus and cardiovascular disease. In these subjects, abdominal adipose tissue is a source of inflammatory cytokines such as tumor necrosis factor-alpha, known to promote insulin resistance. The presence of inflammatory cytokines together with the well-documented increased risk for… CONTINUE READING
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Prevalence of the metabolic syndrome is increased in rheumatoid arthritis and is associated with coronary

  • A Ehling, A Schäffler, +9 authors U Müller-Ladner
  • ATHEROSCLEROSIS
  • 2008

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