Metabolic syndrome in aboriginal Canadians: prevalence and genetic associations.

  title={Metabolic syndrome in aboriginal Canadians: prevalence and genetic associations.},
  author={Rebecca L. Pollex and Anthony J. G. Hanley and Bernard Zinman and Stewart B Harris and Hafiz M. R. Khan and Robert A Hegele},
  volume={184 1},
OBJECTIVES The prevalence rates of type 2 diabetes (T2DM) and coronary heart disease (CHD) in Ontario Oji-Cree are among the world's highest. Since metabolic syndrome (MetS) increases risk of T2DM and CHD, we characterized prevalence and putative genetic determinants of MetS in Oji-Cree. METHODS AND RESULTS In 515 adult (> or = 18 years old) and 115 adolescent (< 18 years old) Oji-Cree subjects, using the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria… CONTINUE READING


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