Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation.

@article{Dandona2005MetabolicSA,
  title={Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation.},
  author={Paresh Dandona and Ahmad Aljada and Ajay Chaudhuri and Priya Ranjan Mohanty and Rajesh Garg},
  journal={Circulation},
  year={2005},
  volume={111 11},
  pages={1448-54}
}
The original description of the metabolic syndrome by Reaven1 consisted of obesity, insulin resistance, hypertension, impaired glucose tolerance or diabetes, hyperinsulinemia and dyslipidemia characterized by elevated triglyceride, and low HDL concentrations. All of the features described above are risk factors for atherosclerosis, and thus, metabolic syndrome constituted a significant risk for coronary heart disease2–5 (Table). The features of obesity/overweight and insulin resistance also… CONTINUE READING
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