Metabolic syndrome, age‐associated neuroendocrine disorders, and dysregulation of tryptophan—kynurenine metabolism

@article{Oxenkrug2010MetabolicSA,
  title={Metabolic syndrome, age‐associated neuroendocrine disorders, and dysregulation of tryptophan—kynurenine metabolism},
  author={G. Oxenkrug},
  journal={Annals of the New York Academy of Sciences},
  year={2010},
  volume={1199}
}
  • G. Oxenkrug
  • Published 2010
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
  • The neuroendocrine theory of aging identified a cluster of conditions (hypertension, obesity, dyslipidemia, diabetes type 2, menopause, late onset depression, vascular cognitive impairment, impairment of immune defense, and some forms of cancer, e.g., breast and prostate) as age‐associated neuroendocrine disorders (AAND). Obesity, dyslipidemia, hypertension, and type 2 diabetes were later described as metabolic syndromes (MetS). Chronic inflammation is currently considered as a common feature… CONTINUE READING
    134 Citations
    Peripheral Tryptophan - Kynurenine Metabolism Associated with Metabolic Syndrome is Different in Parkinson's and Alzheimer's Diseases.
    • 9
    • PDF
    IDO chronic immune activation and tryptophan metabolic pathway: A potential pathophysiological link between depression and obesity
    • 31
    • Highly Influenced
    • PDF
    Metabolic syndrome--from the neurotrophic hypothesis to a theory.
    • 28
    Metabolic syndrome as a risk factor for neurological disorders
    • 137
    Kynurenines and vitamin B6: link between diabetes and depression.
    • 22

    References

    SHOWING 1-10 OF 133 REFERENCES
    Genetic and Hormonal Regulation of Tryptophan–Kynurenine Metabolism
    • G. Oxenkrug
    • Psychology, Medicine
    • Annals of the New York Academy of Sciences
    • 2007
    • 112
    The metabolic syndrome and inflammation.
    • 200
    Chronic immune activation underlies morbid obesity: is IDO a key player?
    • 72
    The emergence of the metabolic syndrome with menopause.
    • M. C. Carr
    • Medicine
    • The Journal of clinical endocrinology and metabolism
    • 2003
    • 1,101
    • PDF
    Insulin resistance as the underlying cause for the metabolic syndrome.
    • 173
    The metabolic syndrome is associated with circulating adipokines in older adults across a wide range of adiposity.
    • 94
    • PDF