Metabolic studies with promagnon, methylclostebol and methasterone in the uPA+/+-SCID chimeric mice.

Abstract

The chimeric uPA(+/+)-SCID mouse model, transplanted with human hepatocytes, was previously validated as an alternative tool to study in vivo the human steroid metabolism. This humanized mouse model was now applied, in the framework of anti-doping research, to test different nutritional supplements containing steroids. These steroids, intentionally or… (More)
DOI: 10.1016/j.jsbmb.2011.06.010

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