Metabolic status of pluripotent cells and exploitation for growth in stirred suspension bioreactors.

@article{Day2013MetabolicSO,
  title={Metabolic status of pluripotent cells and exploitation for growth in stirred suspension bioreactors.},
  author={Brad Day and D. E. Rancourt},
  journal={Biotechnology & genetic engineering reviews},
  year={2013},
  volume={29},
  pages={24-30}
}
Pluripotent stem cells are of great interest in the field of regenerative medicine. Recent studies have shown that they maintain a glycolytic metabolic status while pluripotent and wholesale changes to mitochondrial and metabolic profile occur during differentiation. This article reviews the process and how this may be exploited in a stirred suspension bioreactor for rapid growth while maintaining pluripotency.