• DOI:10.1016/0022-5193(69)90015-0
Corpus ID: 16927629

Metabolic stability and epigenesis in randomly constructed genetic nets.

@article{Kauffman1969MetabolicSA,
  title={Metabolic stability and epigenesis in randomly constructed genetic nets.},
  author={S. Kauffman},
  journal={Journal of theoretical biology},
  year={1969},
  volume={22 3},
  pages={
          437-67
        }
}

• S. Kauffman
• Published 1969
• Biology, Medicine
• Journal of theoretical biology

Abstract Proto-organisms probably were randomly aggregated nets of chemical reactions. The hypothesis that contemporary organisms are also randomly constructed molecular automata is examined by modeling the gene as a binary (on-off) device and studying the behavior of large, randomly constructed nets of these binary “genes”. The results suggest that, if each “gene” is directly affected by two or three other “genes”, then such random nets: behave with great order and stability; undergo behavior… Expand

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