Metabolic responses to BRL37344 and clenbuterol in soleus muscle and C2C12 cells via different atypical pharmacologies and beta2-adrenoceptor mechanisms.

@article{Ngala2008MetabolicRT,
  title={Metabolic responses to BRL37344 and clenbuterol in soleus muscle and C2C12 cells via different atypical pharmacologies and beta2-adrenoceptor mechanisms.},
  author={Robert A. Ngala and Jacqueline O'Dowd and Steven J Y Wang and Ak Agarwal and Claire J. Stocker and Michael Anthony Cawthorne and Jonathan R. S. Arch},
  journal={British journal of pharmacology},
  year={2008},
  volume={155 3},
  pages={395-406}
}
BACKGROUND AND PURPOSE Picomolar concentrations of the beta3-adrenoceptor agonist BRL37344 stimulate 2-deoxyglucose uptake in soleus muscle via undefined receptors. Higher concentrations alter uptake, apparently via beta2-adrenoceptors. Effects of BRL37344 and beta2-adrenoceptor agonists are compared. EXPERIMENTAL APPROACH Mouse soleus muscles were… CONTINUE READING