Metabolic rate in the right amygdala predicts negative affect in depressed patients.

  title={Metabolic rate in the right amygdala predicts negative affect in depressed patients.},
  author={Heather C. Abercrombie and Stacey M. Schaefer and Christine L. Larson and Terrence R. Oakes and Kristen A. Lindgren and James E. Holden and Susan B. Perlman and P A Turski and Dean D Krahn and Ruth M. Benca and Richard J. Davidson},
  volume={9 14},
The role of the amygdala in major depression was investigated. Resting regional cerebral metabolic rate (rCMRglu) was measured with [18F]fluorodeoxyglucose positron emission tomography (PET) in two samples of subjects using two different PET cameras. The samples consisted of 10 and 17 medication-free depressives and 11 and 13 controls, respectively. Using coregistration of PET and magnetic resonance images, regions were individually delineated for the amygdala and thalamus, the latter of which… CONTINUE READING

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