Metabolic profiles of minimally absorbed orlistat in obese/overweight volunteers.

@article{Zhi1996MetabolicPO,
  title={Metabolic profiles of minimally absorbed orlistat in obese/overweight volunteers.},
  author={Jianguo Zhi and Adrian Melia and Christoph Funk and A Viger-Chougnet and G{\'e}rard Hopfgartner and Berthold Lausecker and Ke Wang and J. Struthers Fulton and Luigi Gabriel and Thomas Mulligan},
  journal={Journal of clinical pharmacology},
  year={1996},
  volume={36 11},
  pages={
          1006-11
        }
}
To determine the metabolic profile of minimally absorbed orlistat in obese/overweight patients, an open-label, single-dose study was performed in eight obese/overweight volunteers between 23 and 68 years of age. Each subject received a single oral dose of 360 mg orlistat containing approximately 400 muCi of 14C-labeled orlistat. Serial blood samples were collected at specified times over 10 hours after administration of orlistat for determination of total radioactivity, unchanged orlistat, and… CONTINUE READING
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