Metabolic products of microorganisms. 264. Exfoliamycin and related metabolites, new naphthoquinone antibiotics from Streptomyces exfoliatus.

  title={Metabolic products of microorganisms. 264. Exfoliamycin and related metabolites, new naphthoquinone antibiotics from Streptomyces exfoliatus.},
  author={Olivier Potterat and Hans Z{\"a}hner and C Volkmann and Axel Zeeck},
  journal={The Journal of antibiotics},
  volume={46 2},
In the course of our chemical screening program, we observed that Streptomyces exfoliatus (strain Tii 1424) synthesized numerous quinoid pigments when rotary shaker cultures were supplemented with Amberlite XAD-1180. We report here on the isolation and structure elucidation of three antibiotics, which were shown to be new naphthoquinone C-glycosides (2~4). After isolation from a soil sample collected in Turkey, the strain Tii 1424 was cultivated in 500ml baffled Erlenmeyer flasks containing… 
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