Metabolic perturbance in autism spectrum disorders: a metabolomics study.

  title={Metabolic perturbance in autism spectrum disorders: a metabolomics study.},
  author={X. T. Ming and Thomas P. Stein and Virginia Barnes and Nelson Rhodes and Lining Guo},
  journal={Journal of proteome research},
  volume={11 12},
Autism spectrum disorders (ASD) are a group of biological disorders with associated metabolic derangement. This study aimed to identify a pattern of metabolic perturbance in ASD using metabolomics in urinary specimens from 48 children with ASD and 53 age matched controls. Using a combination of liquid- and gas-chromatography-based mass spectrometry, we detected the levels of 82 metabolites (53 of which were increased) that were significantly altered between the ASD and the control groups using… CONTINUE READING
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