Metabolic pathways in immune cell activation and quiescence.

@article{Pearce2013MetabolicPI,
  title={Metabolic pathways in immune cell activation and quiescence.},
  author={Erika L Pearce and Edward J. Pearce},
  journal={Immunity},
  year={2013},
  volume={38 4},
  pages={633-43}
}
Studies of immune system metabolism ("immunometabolism") segregate along two paths. The first investigates the effects of immune cells on organs that regulate whole-body metabolism, such as adipose tissue and liver. The second explores the role of metabolic pathways within immune cells and how this regulates immune response outcome. Distinct metabolic pathways diverge and converge at many levels, and, therefore, cells face choices as to how to achieve their metabolic goals. There is interest in… CONTINUE READING
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