Metabolic pathfinding using RPAIR annotation.

@article{Faust2009MetabolicPU,
  title={Metabolic pathfinding using RPAIR annotation.},
  author={Karoline Faust and Didier Croes and Jacques van Helden},
  journal={Journal of molecular biology},
  year={2009},
  volume={388 2},
  pages={
          390-414
        }
}
  • Karoline Faust, Didier Croes, Jacques van Helden
  • Published in Journal of molecular biology 2009
  • Medicine, Biology
  • Metabolic databases contain information about thousands of small molecules and reactions, which can be represented as networks. In the context of metabolic reconstruction, pathways can be inferred by searching optimal paths in such networks. A recurrent problem is the presence of pool metabolites (e.g., water, energy carriers, and cofactors), which are connected to hundreds of reactions, thus establishing irrelevant shortcuts between nodes of the network. One solution to this problem relies on… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 57 REFERENCES

    NeAT: a toolbox for the analysis of biological networks, clusters, classes and pathways

    VIEW 2 EXCERPTS

    Global reconstruction of the human metabolic network based on genomic and bibliomic data.

    VIEW 1 EXCERPT

    KEGG for linking genomes to life and the environment