Metabolic modelling of microbes: the flux-balance approach.

  title={Metabolic modelling of microbes: the flux-balance approach.},
  author={Jeremy S. Edwards and Markus W. Covert and Bernhard O. Palsson},
  journal={Environmental microbiology},
  volume={4 3},
One area of active research in this area has focused on bacterial metabolism (van Gulik and Heijnen, 1995; Liao et al., 1996; Lee et al., 1997; Sauer et al., 1998; Edwards and Palsson, 1999; Sauer and Bailey, 1999; Schilling et al., 1999; Edwards and Palsson, 2000a, b; Schilling et al., 2000; Edwards et al., 2001a, b). Genomic information, coupled with biochemical and strain-specific information, has been used to reconstruct whole-cell metabolic networks for sequenced organisms (Edwards and… CONTINUE READING
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