Metabolic markers of developmental competence for in vitro-matured mouse oocytes.

@article{Preis2005MetabolicMO,
  title={Metabolic markers of developmental competence for in vitro-matured mouse oocytes.},
  author={Kimberly A Preis and George Seidel and David K Gardner},
  journal={Reproduction},
  year={2005},
  volume={130 4},
  pages={475-83}
}
In vitro maturation of oocytes has enormous potential in assisted reproductive technology, but its use has been limited due to insufficient knowledge of oocyte physiology during this dynamic period and lack of an adequate maturation system. The aim of this study was to characterize the metabolic profiles of three groups of oocytes throughout maturation: cumulus-oocyte complexes (COCs), denuded oocytes, and denuded oocytes co-cultured with cumulus cells. Mouse oocytes were collected from 28-day… CONTINUE READING

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