Metabolic interactions of alcohol and folate.

  title={Metabolic interactions of alcohol and folate.},
  author={Charles H. Halsted and Jesus A. Villanueva and Angela M. Devlin and Carol J Chandler},
  journal={The Journal of nutrition},
  volume={132 8 Suppl},
The goals and objectives of these studies, conducted over the past 30 y, were to determine: a) how chronic alcoholism leads to folate deficiency and b) how folate deficiency contributes to the pathogenesis of alcoholic liver disease (ALD). The intestinal absorption of folic acid was decreased in binge drinking alcoholics and, prospectively, in volunteers fed alcohol with low folate diets. Monkeys fed alcohol for 2 y developed decreased hepatic folate stores, folic acid malabsorption and… CONTINUE READING
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