Metabolic inflexibility is a common feature of impaired fasting glycaemia and impaired glucose tolerance

@article{Frch2010MetabolicII,
  title={Metabolic inflexibility is a common feature of impaired fasting glycaemia and impaired glucose tolerance},
  author={Kristine F{\ae}rch and Allan Vaag},
  journal={Acta Diabetologica},
  year={2010},
  volume={48},
  pages={349-353}
}
Metabolic flexibility reflects the ability to switch from lipid to carbohydrate oxidation during insulin stimulation. Impaired metabolic flexibility is related to insulin resistance and type 2 diabetes, but whether metabolic flexibility is impaired in individuals with the pre-diabetic states isolated impaired fasting glycaemia (i-IFG) and isolated impaired glucose tolerance (i-IGT) is unknown. Using the gold standard euglycaemic hyperinsulinaemic clamp technique combined with indirect… CONTINUE READING

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