Metabolic implications of dietary trans-fatty acids.

  title={Metabolic implications of dietary trans-fatty acids.},
  author={Suzanne E. Dorfman and Didier Laurent and John S Gounarides and Xue Li and Tara L Mullarkey and Erik C Rocheford and Farid Sari-Sarraf and Erica A Hirsch and Thomas E Hughes and S. Renee Commerford},
  volume={17 6},
Dietary trans-fatty acids are associated with increased risk of cardiovascular disease and have been implicated in the incidence of obesity and type 2 diabetes mellitus (T2DM). It is established that high-fat saturated diets, relative to low-fat diets, induce adiposity and whole-body insulin resistance. Here, we test the hypothesis that markers of an obese, prediabetic state (fatty liver, visceral fat accumulation, insulin resistance) are also worsened with provision of a low-fat diet… CONTINUE READING