Metabolic imaging of rat brain during pharmacologically-induced tinnitus

@article{Paul2009MetabolicIO,
  title={Metabolic imaging of rat brain during pharmacologically-induced tinnitus},
  author={A. K. Paul and E. Lobarinas and R. Simmons and David S. Wack and John C. Luisi and J. Spernyak and R. Mazurchuk and H. Abdel-Nabi and R. Salvi},
  journal={NeuroImage},
  year={2009},
  volume={44},
  pages={312-318}
}
Although much is known about the perceptual characteristics of tinnitus, its neural origins remain poorly understood. We investigated the pattern of neural activation in central auditory structures using positron emission tomography (PET) imaging in a rat model of salicylate-induced tinnitus. Awake rats were injected with the metabolic tracer, fluorine-18 fluorodeoxyglucose (FDG), once in a quiet state (baseline) and once during salicylate-induced tinnitus. Tinnitus was verified using a… CONTINUE READING

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