Metabolic genotypes and risk for colorectal cancer.

  title={Metabolic genotypes and risk for colorectal cancer.},
  author={Wendy J Butler and Philip Ryan and Ian C. Roberts-Thomson},
  journal={Journal of gastroenterology and hepatology},
  volume={16 6},
BACKGROUND Inherited polymorphisms that influence carcinogen metabolism or the composition of bile may influence the risk for the development of colorectal cancer. METHODS The frequency of polymorphisms involving N-acetyltransferase 1 (NAT1), NAT2, cytochrome P450 1A1 (CYP1A1), CYP2D6, CYP2E1, glutathione S-transferase M1 (GSTM1), GSTT1 and apolipoprotein E were compared in 219 white adults with sporadic colorectal cancer and 200 white controls attending for blood donation at a blood bank… CONTINUE READING
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