Metabolic gene polymorphism frequencies in control populations.

@article{Garte2001MetabolicGP,
  title={Metabolic gene polymorphism frequencies in control populations.},
  author={Seymour J. Garte and Laura Gaspari and A K Alexandrie and Christine A Ambrosone and Herman Autrup and Judith L. Autrup and Helena Baranova and Lisa Bathum and Simone Benhamou and Paolo Boffetta and Christine Bouchardy and Katja Breskvar and Jurgen Brockmoller and Ingolf Cascorbi and Margie Lee Clapper and Christiane Coutelle and Ann Daly and M Dell'omo and Vita Dol{\vz}an and Carolyn M. Dresler and Anthony A Fryer and Aage Haugen and David W Hein and Allan Hildesheim and Ari P Hirvonen and Ling Ling Hsieh and Magnus Ingelman-Sundberg and Ivan Kalina and Daehee Kang and Masahiro Kihara and Chikako Kiyohara and Pierre Kremers and Philip Lazarus and Lo{\"i}c Le Marchand and Maria Celeste Lechner and Esther M M Van Lieshout and Stephanie London and Johannes Jan Manni and Christine M. Maugard and Shunji Morita and Valle Nazar-Stewart and Kazumasa Noda and Yoshio Oda and Fritz F. Parl and Roberta Pastorelli and Iren{\'e} Persson and Wilbert H. M. Peters and Agneta Rannug and Timothy Rebbeck and Angela Risch and Liliane Roelandt and Marjorie Romkes and David Ryberg and J{\'a}n {\vS}alagovi{\vc} and Bernadette Schoket and Janeric Seideg{\aa}rd and Peter G. Shields and Edith Sim and Daniel Sinnet and Richard C. Strange and Isabel St{\"u}cker and Haruhiko Sugimura and Jordi To-Figueras and Paolo Vineis and Mimi C. Yu and Emanuela Taioli},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2001},
  volume={10 12},
  pages={1239-48}
}
Using the International Project on Genetic Susceptibility to Environmental Carcinogens (GSEC) database containing information on over 15,000 control (noncancer) subjects, the allele and genotype frequencies for many of the more commonly studied metabolic genes (CYP1A1, CYP2E1, CYP2D6, GSTM1, GSTT1, NAT2, GSTP, and EPHX) in the human population were determined. Major and significant differences in these frequencies were observed between Caucasians (n = 12,525), Asians (n = 2,136), and Africans… CONTINUE READING
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