Metabolic flux in cellulose batch and cellulose-fed continuous cultures of Clostridium cellulolyticum in response to acidic environment.

@article{Desvaux2001MetabolicFI,
  title={Metabolic flux in cellulose batch and cellulose-fed continuous cultures of Clostridium cellulolyticum in response to acidic environment.},
  author={Micka{\"e}l Desvaux and Emmanuel Guedon and Henri Petitdemange},
  journal={Microbiology},
  year={2001},
  volume={147 Pt 6},
  pages={1461-71}
}
Clostridium cellulolyticum, a nonruminal cellulolytic mesophilic bacterium, was grown in batch and continuous cultures on cellulose using a chemically defined medium. In batch culture with unregulated pH, less cellulose degradation and higher accumulation of soluble glucides were obtained compared to a culture with the pH controlled at 7.2. The gain in cellulose degradation achieved with pH control was offset by catabolite production rather than soluble sugar accumulation. The pH-controlled… CONTINUE READING
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