Metabolic flexibility of Clostridium acetobutylicum in response to methyl viologen addition

  title={Metabolic flexibility of Clostridium acetobutylicum in response to methyl viologen addition},
  author={S. Peguin and Gerard Goma and Patrick Delorme and Philippe Soucaille},
  journal={Applied Microbiology and Biotechnology},
Batch cultures of Clostridium acetobutylicum, were examined with 0, 0.1 and 1 mM methyl viologen addition at four different controlled pH values (between 4.5 and 6.5). Methyl viologen addition diverted the electron flow: reducing equivalents normally released as molecular hydrogen were directed towards NAD(P)H formation. Production of butanol, the most reduced non-gaseous product, was sharply increased (0.65 mol/mol glucose) at the expense of acetone and butyric and acetic acids. In addition to… CONTINUE READING


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How neutral red modified carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH

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