Metabolic fate of N,N-dibutylnitrosamine in the rat.


The metabolic fate of N,N-dibutylnitrosamine (DBN) was studied in the rat, to elucidate the possibility of a correlation between its metabolism and its organotropic carcinogenicity to the urinary bladder and other organs. It was extensively metabolized in the rat, no unchanged DBN being found in the urine. DNA underwent metabolic transformation in at least… (More)


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@article{Suzuki1980MetabolicFO, title={Metabolic fate of N,N-dibutylnitrosamine in the rat.}, author={Etsu Suzuki and Masahiko Okada}, journal={Gan}, year={1980}, volume={71 6}, pages={863-70} }